We are one of the first laboratories in Europe to comply with the latest European Pharmacopoeia (Ph Eur) monographs of 18 amino acids, analysing ninhydrin-positive substances by High Performance Liquid Chromatography (HPLC).
The recent changes to the ninhydrin-positive substances Ph Eur test method affect the following monographs:
- Alanine
- Arginine
- Arginine hydrochloride
- Cysteine hydrochloride monohydrate
- Cysteine
- Glycine
- Histidine
- Histidine hydrochloride monohydrate
- Isoleucine
- Leucine
- Lysine hydrochloride
- Phenylalanine
- Proline
- Serine
- Threonine
- Tryptophan
- Tyrosine
- Valine
The Ph Eur general monograph 2.2.56. Method 1 is harmonized with the following chapters:
– USP Biotechnology-Derived Articles – Amino Acid Analysis – Method 1,
– JP: 2.04 Amino Acid Analysis of Proteins – Method 1
Explore some of the techniques we commonly use for the testing of ninhydrin positive substances:
