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Techniques

Butterworth Laboratories have a wide range of instrumental and classical techniques available:

Resources:


Chromatography

Fitted with a variety of detectors, the laboratories essentially have three instrument techniques available, all of which are useful for both qualitative and quantitative analysis.

These are:


• Gas Chromatography (GC) with the following detectors: MS - Mass Spectrometry
FID - Flame Ionisation
ECD - Electron Capture
TCD - Thermal Conductivity
NPD - Nitrogen, Phosphorus

Widely used, almost entirely for organic materials, the technique is rapid, simple and can cope with very complex mixtures (100 or more components) and very small samples (nanograms). In addition to the various detectors, the laboratory has a number of automated headspace samplers, and a heated gas injection valve.

• Liquid Chromatography (HPLC) with the following detectors:

UV (inc. Diode Array)
Fluorescence
RI (Refractive Index)


• Ion Chromatography (IC) with the following detectors: Conductivity
PAD (Pulsed Amperometric)
UV
RI (Refractive Index)

Both these techniques are widely used for organic and inorganic materials. They are especially useful for checks on purity, to monitor reactions and production processes and to characterise complex materials.

In addition classical techniques available include:

• Thin Layer Chromatography (TLC) and Paper Chromatography

Used mainly for qualitative purposes, almost any mixture can be at least partially resolved by one of these techniques. It is ideally suited to quality control, purity checks, clinical diagnosis and forensic tests.

• Column Chromatography

Less commonly used than the other techniques as a stand-alone technique.